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Cleaning Science

Strengthen your risk-based approach to cleaning validation.

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CIP/SIP, Cleaning Validation, and Risk Assessment Services for Pharmaceutical Manufacturing

Optimize cleaning processes, ensure regulatory compliance, and maximize efficiency.

Expert CIP/SIP Design, Implementation and Monitoring Services.

Just as cleaning has been a core part of Hyde's business since our founding in 1993, so too has been the accompanying science.

Hyde integrates cleaning science into every phase of your program, from developmental studies to hydraulic balancing and cleaning cycle development to cleaning validation and ongoing monitoring. Regardless of which phase of your cleaning program requires attention, Hyde has a team of experts to provide support.
Whether you have an established cleaning program or one under development, Hyde can help.
  • Cleaning validation strategy and masterplan development
  • Cleaning program gap assessment
  • Cleaning process development lab studies
Engineering
  • Facility and Process Design
  • Capacity Analysis and Optimization of Clean-in-place (CIP) and Steam-in-place (SIP) Circuits
  • Process Equipment aseptic and hygienic Design Reviews
  • Aging Facility Remediation and Redesign
  • CIP Skid Specification and Design
  • Development of CIP/SIP Circuitry and Associated Documentation
Site Engineering
  • CIP Cycle Development
  • SIP Cycle Development
Cleaning and Sterilization Validation
  • Development and execution of protocols
  • Concise and accurate reporting

Reach out to the Hyde E+C team for assistance in establishing or optimizing your cleaning programs.

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Expert Advice

#sustainability

CIP cycle optimization is probably the single biggest lever available to any facility striving for sustainability, with large project ROIs measurable in days, not months or years.

Kenneth Pierce, P.h.D.
Technical SME, Europe, Cleaning Validation & Cleaning Science

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Explore Hyde E+C Services

Expertise in providing tailored solutions from concept to operational systems.

Analytical Laboratory

Ensure methods are validated and your cleaning program is backed by data, with access to the best in the business.
  • Method Validation
  • Recovery Studies
  • Cleaning Optimization
  • MACO Limits Determination

CQV Services

Commissioning, Qualification and Validation. Offering complete support across all industries we serve, spanning from black utilities to purification systems.
  • Cleaning Program Development & support
  • Site Engineering Services
  • Engineering Design Services

Engineering

Skilled at taking your project from concept to operation systems.
  • Feasibility studies
  • Conceptual, Basic and Detailed Design
  • Remediation Studies
  • Assessments

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