Cleaning Science

Biologics Facility
Cleaning Optimization

Project

Outcome
1

40% reduction in caustic usage

2

50% reduction in overall cleaning times

3

65% reduction in WFI use

4

800 man-hour reduction in setup

Project

Goals

Double capacity for new products by:

Project

at a Glance

Hyde Engineering + Consulting reduced caustic usage by 40%, overall cleaning times by 50%, and WFI use by 65%. This saved over 800 man-hour reduction in setup.

About

Hyde Engineering + Consulting

Hyde Engineering + Consulting has been a global leader in process system design, commissioning, and FDA compliance for regulated industries since 1993.

Our Results

40 - 60%

Reduction in Chemical Consumption

45 - 70%

Increase in CIP System Availability

40 - 70%

Reduction in Water Consumption

1.5 - 2.5x

Increase in Manufacturing Throughput

Project

Components

System Flowrate Analysis

Solvent Selection Rationalization

Cleaning Cycle Analysis