Engineering

Drug Substance Manufacturing Facility Design EPCMV Cell Culture
EPCMV Cell Culture

Project

Description

This was a Greenfield multi-product drug substance facility. The facility was designed with hybrid equipment, developing an optimum mix between single use technology and stainless steel equipment.

The equipment systems included media prep, seed and production bioreactors, harvest, buffer prep and hold, upstream purification, downstream purification, bulk drug formulation and fill, and buffer preparation.

Scope

Of Services

Solutions, Results,

and Accomplishments
Current Equipment ID# (PFD Rev 1.0) Type Description Capacity Specified Unit Vessel / Bag (F/M/D) Tote / Rack Mag Stirrer (Bag)
BRV-01 Disposable Bioreactor 50 L D N/A Y
BRV-02 Disposable Bioreactor 200 L D N/A Y
BRV-03 SS Bioreactor 1000 L F N/A N
BRV-04 SS Bioreactor 5000 L F N/A N
BRV-05 SS Bioreactor 5000 L F N/A N
RSV-01 Tank-SS Resin Slurry Tank 700 L F N/A N
Deleted Tank-SS Pool Mix Tank (ProA) 3000 L F N/A N
MPV-02 Tank-SS Media Prep Mix Tank 4500 L F N/A N
MPV-01 Tank-SS Media Prep Mix Tank 1500 L F N/A N
MPV-03 Tank-SS Media Prep Mix Tank 300 L F N/A N