Digital Image Processing for Bench Scale Cleanability Studies

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By Kelly Scalva, Steve Buckingham, & Keith Bader

This article is based on a presentation given at the ISPE 2013 Annual Meeting and presents an overview of a novel quantitative method utilizing imaging software combined with tightly controlled variables in lighting, angle, and distance, quantifies the amount of process residue on a surface using high-resolution photographs, to produce statistically significant data.

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